Liver enzymes in human undernutrition

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Liver enzymes in human undernutrition.

‘The study of nutrition and the study of enzymes represent two sides of the same coin’ (Green, 1946). This statement is specially applicable in cases of nutritional oedema and kwashiorkor, both being states of protein malnutrition. Since enzymes are protein in nature it is to be expected that protein malnutrition will lead to a diminution in the quantity of enzymes. Acute starvation in rats pro...

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Effect of Acesulfame k on Liver Enzymes and Liver Tissue in Immature Male Rats

  Background and purpose: Artificial sweeteners are increasingly used in food products, so, it is necessary to study the effects of these additives on liver. Materials and methods: In this experimental study, 30 immature male rats were divided into five groups (n=6 per group) and acesulfame k at 50, 100, 200, and 400 mg/kg were injected intraperitoneally to all groups for 30 days. One and 30 d...

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Stereoselective metabolism of lansoprazole by human liver cytochrome P450 enzymes.

The stereoselective metabolism of lansoprazole enantiomers was evaluated by incubation of human liver microsomes and cDNA-expressed cytochrome p450 (p450) enzymes to understand and predict their stereoselective disposition in humans in vivo. The intrinsic clearances (Clint) of the formation of both hydroxy and sulfone metabolites from S-lansoprazole were 4.9- and 2.4-fold higher than those from...

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Experimental Liver Necrosis; Ii. Enzymes

1. The presence of blood serum has a decided inhibitory effect on autolysis. Thus in the normal unwashed organs the non-coagulable nitrogen increase was 100 to 300 per cent., while in the washed it amounted to 450 per cent. The washed necrotic livers showed an increase of from 600 to 850 per cent., while that of the unwashed necrotic was only slightly above the normal unwashed. 2. While the ini...

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Intracellular Proteolytic Enzymes of Liver

In all living tissues, protein constituents are continually being broken down within the body cells and protein decomposition products are excreted. If any or all of the processes of degradation occurring during life are the work of enzymes, we should expect to be able to demonstrate the existence of these enzymes in the tissues after death. The occurrence of such proteolytic enzymes was first ...

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ژورنال

عنوان ژورنال: British Journal of Nutrition

سال: 1958

ISSN: 0007-1145,1475-2662

DOI: 10.1079/bjn19580002